BDBM50331094 4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamide::4-(3-chloro-4-(N'-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamide::CHEMBL1289601::E-7080::Lenvatinib mesilate::Lenvima::lenvatinib
SMILES COc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O
InChI Key InChIKey=WOSKHXYHFSIKNG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50331094
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system using Ulight-JA...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataKd: 2.10nMAssay Description:Binding affinity to VEGFR2 (unknown origin) by proteros reporter displacement assayMore data for this Ligand-Target Pair